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Re: Buy 4-AcO-DMT

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Subject: Re: Buy 4-AcO-DMT
From: info.tri...@gmail.com (Trippin Bros)
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by: Trippin Bros - Sun, 27 Aug 2023 01:24 UTC

BUY 4-ACO DMT | 4 ACO DMT FOR SALE ONLINE | BEST 4 ACO DMT FOR SALE ONLINE |QUALITY 4 ACO DMT FOR SALE | BEST PLACE TO BUY 4 ACO DMT

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4-Acetoxy-N,N-dimethyltryptamine (psilacetin or 4-AcO-DMT) is a synthetic psychedelic tryptamine with close structural similarities to the “magic mushroom” molecules psilocybin and psilocin.

It was developed by the inventor of LSD Albert Hofmann, along with Franz Troxler, for Sandoz Ltd., the company that patented the drug in 1963 (incidentally the same year their LSD patents expired).
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Of the many “grey market” research chemicals out there, 4-AcO-DMT is probably among the safest. At macrodoses, its effects are comparable – although in some ways rather different – to those of psilocybin or psilocin. Most users report a full range of psychedelic visual effects, from color enhancement to vivid hallucinations, along with euphoria, ego loss, and mystical or religious experiences.
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And, as with psilocybin, microdoses have been linked to:

Increased empathy and sociability
Introspection
Mood enhancement
Visual clarity and color enhancement
Motivation and energy
Relaxation, peace, and contentedness
Mental clarity and focus
THE SCIENCE OF 4-ACO-DMT MICRODOSING

4-AcO-DMT is also known as O-Acetylpsilocin; that is, the O-acetylated form or ester of psilocin (4-HO-DMT) – psilocybin (4-PO-DMT) being the O-phosphorylated form. In other words, 4-AcO-DMT has the same basic structure as both psilocin and psilocybin, but with an acetoxy group bonded to its indole ring.
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Like psilocybin, 4-AcO-DMT is considered a prodrug of psilocin, converting into the latter through metabolism by the body. Pharmacologist David Nichols even went so far as to advocate its replacement of psilocybin in psilocin research, since 4-AcO-DMT is by far the easier ester to synthesize.

The prodrug theory is not without its critics, however. According to some, the immediate psychoactivity of 4-AcO-DMT when injected or smoked (i.e. when bypassing the metabolism), as well as its higher average dose than psilocin, suggests the compound is uniquely psychoactive in its own right and not just, or even necessarily, as a metabolic precursor to psilocin.
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There are subjective differences too. While some consider the effects of 4-AcO-DMT to be identical to those of psilocybin mushrooms, others point out differences. They may find it mellower, more forgiving, or less ego-disruptive than mushrooms, while some even liken it to DMT, especially at high doses.

Still, it’s important to note that naturally occurring levels of psilocybin and psilocin vary significantly even between mushrooms of the same species, so no two experiences are likely to be the same. They also tend to be accompanied by other alkaloids, such as baeocystin and norbaeocystin, which have presumed effects of their own. 4-AcO-DMT, meanwhile, has no such variability, so it ensures greater consistency for microdosing at least, even if its subjective effects are different from psilocybin mushrooms.
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Given its chemical similarities to psilocin, though, we can safely assume that 4-AcO-DMT has roughly the same mechanism of action – primarily activating the 5-HT2A serotonin receptors.

Much of what we understand about how psychedelics work involves serotonin, a chemical that keeps our brains ticking. It is one of the most important neurotransmitters, affecting nearly everything we do – from how we feel to how we process information.
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Indeed, much like other classical psychedelics (including LSD), psilocybin, psilocin, and 4-AcO-DMT actually share a similar molecular structure to serotonin. So while SSRI (selective serotonin reuptake inhibitor) antidepressants work to alleviate low mood by increasing serotonin levels in the brain, 4-AcO-DMT would be expected to work more directly by actually mimicking serotonin itself, and stimulating serotonin receptors.

Subject	Replies	Author
Buy 4-AcO-DMT By: psychedelic minds on Fri, 25 Aug 2023	2	psychedelic minds