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interests / soc.culture.bulgaria / Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

SubjectAuthor
* Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The roleNick
`* Re: Innate immune suppression by SARS-CoV-2 mRNA vacРадостина
 `* Re: Innate immune suppression by SARS-CoV-2 mRNA vacIvaylo Ivanov
  `* Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: TheNick
   `* Re: Innate immune suppression by SARS-CoV-2 mRNA vacIvaylo Ivanov
    `- Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: TheNick

1
Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

<t3hjb3$l5f$1@gioia.aioe.org>

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From: ddantg...@mail.ru (Nick)
Newsgroups: soc.culture.bulgaria
Subject: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role
of G-quadruplexes, exosomes, and MicroRNAs …
Date: Sun, 17 Apr 2022 17:38:44 -0000 (UTC)
Organization: Aioe.org NNTP Server
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 by: Nick - Sun, 17 Apr 2022 17:38 UTC

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-
quadruplexes, exosomes, and MicroRNAs

https://www.sciencedirect.com/science/article/pii/S027869152200206X

Highlights

• mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike
protein.

• The spike protein is neurotoxic, and it impairs DNA repair mechanisms.

• Suppression of type I interferon responses results in impaired innate
immunity.

• The mRNA vaccines potentially cause increased risk to infectious
diseases and cancer.

• Codon optimization results in G-rich mRNA that has unpredictable complex
effects.

Abstract

The mRNA SARS-CoV-2 vaccines were brought to market in response to the
public health crises of Covid-19. The utilization of mRNA vaccines in the
context of infectious disease has no precedent. The many alterations in
the vaccine mRNA hide the mRNA from cellular defenses and promote a longer
biological half-life and high production of spike protein. However, the
immune response to the vaccine is very different from that to a SARS-CoV-2
infection. In this paper, we present evidence that vaccination induces a
profound impairment in type I interferon signaling, which has diverse
adverse consequences to human health. Immune cells that have taken up the
vaccine nanoparticles release into circulation large numbers of exosomes
containing spike protein along with critical microRNAs that induce a
signaling response in recipient cells at distant sites. We also identify
potential profound disturbances in regulatory control of protein synthesis
and cancer surveillance. These disturbances potentially have a causal link
to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell's
palsy, liver disease, impaired adaptive immunity, impaired DNA damage
response and tumorigenesis. We show evidence from the VAERS database
supporting our hypothesis. We believe a comprehensive risk/benefit
assessment of the mRNA vaccines questions them as positive contributors to
public health.

Graphical abstract

https://ars.els-cdn.com/content/image/1-s2.0-S027869152200206X-ga1.jpg

не изглежда оптимистично.

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

<9a08470b-7057-497a-8eed-2018cfbb1783n@googlegroups.com>

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Subject: Re:_Innate_immune_suppression_by_SARS-CoV-2_mRNA_vac
cinations:_The_role_of_G-quadruplexes,_exosomes,_and_MicroRN
As_…
From: joyrad...@gmail.com (Радостина)
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 by: Радостина - Tue, 19 Apr 2022 00:59 UTC

On Sunday, April 17, 2022 at 10:38:48 AM UTC-7, Nick wrote:
> Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-
> quadruplexes, exosomes, and MicroRNAs
>
> https://www.sciencedirect.com/science/article/pii/S027869152200206X
>
> Highlights
>
> • mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike
> protein.
>
> • The spike protein is neurotoxic, and it impairs DNA repair mechanisms.
>
> • Suppression of type I interferon responses results in impaired innate
> immunity.
>
> • The mRNA vaccines potentially cause increased risk to infectious
> diseases and cancer.
>
> • Codon optimization results in G-rich mRNA that has unpredictable complex
> effects.
>
> Abstract
>
> The mRNA SARS-CoV-2 vaccines were brought to market in response to the
> public health crises of Covid-19. The utilization of mRNA vaccines in the
> context of infectious disease has no precedent. The many alterations in
> the vaccine mRNA hide the mRNA from cellular defenses and promote a longer
> biological half-life and high production of spike protein. However, the
> immune response to the vaccine is very different from that to a SARS-CoV-2
> infection. In this paper, we present evidence that vaccination induces a
> profound impairment in type I interferon signaling, which has diverse
> adverse consequences to human health. Immune cells that have taken up the
> vaccine nanoparticles release into circulation large numbers of exosomes
> containing spike protein along with critical microRNAs that induce a
> signaling response in recipient cells at distant sites. We also identify
> potential profound disturbances in regulatory control of protein synthesis
> and cancer surveillance. These disturbances potentially have a causal link
> to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell's
> palsy, liver disease, impaired adaptive immunity, impaired DNA damage
> response and tumorigenesis. We show evidence from the VAERS database
> supporting our hypothesis. We believe a comprehensive risk/benefit
> assessment of the mRNA vaccines questions them as positive contributors to
> public health.
>
> Graphical abstract
>
> https://ars.els-cdn.com/content/image/1-s2.0-S027869152200206X-ga1.jpg
Аз преди време бях пуснала подобна статия.
Ама нали съм конспиратор, сигурно никой не й обърна внимание. :-)
Упорито се говори че тези ваксини намаляват естествения имунитет,
тепърва ще разберем какво става.
Монтание съвсем сериозно заяви, преди да почине,
всички които са ваксинирани да си направят тест за СПИН,
за всеки случай.

Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

<bcf4c94b-77b7-4ac8-a3db-9310f12cf8ffn@googlegroups.com>

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Subject: Re:_Innate_immune_suppression_by_SARS-CoV-2_mRNA_vac
cinations:_The_role_of_G-quadruplexes,_exosomes,_and_MicroRN
As_…
From: ivaylop...@gmail.com (Ivaylo Ivanov)
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 by: Ivaylo Ivanov - Tue, 19 Apr 2022 13:53 UTC

On Monday, April 18, 2022 at 8:59:42 PM UTC-4, Радостина wrote:
> On Sunday, April 17, 2022 at 10:38:48 AM UTC-7, Nick wrote:
> > Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-
> > quadruplexes, exosomes, and MicroRNAs
> >
> > https://www.sciencedirect.com/science/article/pii/S027869152200206X
> >
> > Highlights
> >
> > • mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike
> > protein.
> >
> > • The spike protein is neurotoxic, and it impairs DNA repair mechanisms.
> >
> > • Suppression of type I interferon responses results in impaired innate
> > immunity.
> >
> > • The mRNA vaccines potentially cause increased risk to infectious
> > diseases and cancer.
> >
> > • Codon optimization results in G-rich mRNA that has unpredictable complex
> > effects.
> >
> > Abstract
> >
> > The mRNA SARS-CoV-2 vaccines were brought to market in response to the
> > public health crises of Covid-19. The utilization of mRNA vaccines in the
> > context of infectious disease has no precedent. The many alterations in
> > the vaccine mRNA hide the mRNA from cellular defenses and promote a longer
> > biological half-life and high production of spike protein. However, the
> > immune response to the vaccine is very different from that to a SARS-CoV-2
> > infection. In this paper, we present evidence that vaccination induces a
> > profound impairment in type I interferon signaling, which has diverse
> > adverse consequences to human health. Immune cells that have taken up the
> > vaccine nanoparticles release into circulation large numbers of exosomes
> > containing spike protein along with critical microRNAs that induce a
> > signaling response in recipient cells at distant sites. We also identify
> > potential profound disturbances in regulatory control of protein synthesis
> > and cancer surveillance. These disturbances potentially have a causal link
> > to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell's
> > palsy, liver disease, impaired adaptive immunity, impaired DNA damage
> > response and tumorigenesis. We show evidence from the VAERS database
> > supporting our hypothesis. We believe a comprehensive risk/benefit
> > assessment of the mRNA vaccines questions them as positive contributors to
> > public health.
> >
> > Graphical abstract
> >
> > https://ars.els-cdn.com/content/image/1-s2.0-S027869152200206X-ga1.jpg
> Аз преди време бях пуснала подобна статия.
> Ама нали съм конспиратор, сигурно никой не й обърна внимание. :-)
Освен хора с конспиративно мислене едва ли някой друг ще обърне внимание на статията
по-горе. Не си струва дори да я коментирам.
> Упорито се говори че тези ваксини намаляват естествения имунитет,
> тепърва ще разберем какво става.
> Монтание съвсем сериозно заяви, преди да почине,
> всички които са ваксинирани да си направят тест за СПИН,
> за всеки случай.
Монтание стана за резил. Жалко, някога беше нещо.

Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

<t3mojs$1iru$1@gioia.aioe.org>

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From: ddantg...@mail.ru (Nick)
Newsgroups: soc.culture.bulgaria
Subject: Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The
role of G-quadruplexes, exosomes, and MicroRNAs …
Date: Tue, 19 Apr 2022 16:39:24 -0000 (UTC)
Organization: Aioe.org NNTP Server
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 by: Nick - Tue, 19 Apr 2022 16:39 UTC

On Tue, 19 Apr 2022 06:53:47 -0700 (PDT), Ivaylo Ivanov wrote:

>> Аз преди време бях пуснала подобна статия.
>> Ама нали съм конспиратор, сигурно никой не й обърна внимание.

> Освен хора с конспиративно мислене едва ли някой друг ще обърне внимание
> на статията по-горе. Не си струва дори да я коментирам.

браво бе, учения -- току-що обяви списание с импакт фактор за
конспиративно. има ли нещо между ушите или караш по добре познатия ти
почин -- „я солженицин не читал, но оссуждаю“?

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

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Subject: Re:_Innate_immune_suppression_by_SARS-CoV-2_mRNA_vac
cinations:_The_role_of_G-quadruplexes,_exosomes,_and_MicroRN
As_…
From: ivaylop...@gmail.com (Ivaylo Ivanov)
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 by: Ivaylo Ivanov - Tue, 19 Apr 2022 19:11 UTC

On Tuesday, April 19, 2022 at 12:39:26 PM UTC-4, Nick wrote:
> On Tue, 19 Apr 2022 06:53:47 -0700 (PDT), Ivaylo Ivanov wrote:
>
> >> Аз преди време бях пуснала подобна статия.
> >> Ама нали съм конспиратор, сигурно никой не й обърна внимание.
> > Освен хора с конспиративно мислене едва ли някой друг ще обърне внимание
> > на статията по-горе. Не си струва дори да я коментирам.
> браво бе, учения -- току-що обяви списание с импакт фактор за
> конспиративно. има ли нещо между ушите или караш по добре познатия ти
> почин -- „я солженицин не читал, но оссуждаю“?

1) "Food and Chemical Toxicology" не е особено престижно списание.
2) Занимавам се с наука и публикувам (и чета) научни сатии редовно - т.е. зная как
"лайна" могат да се публикуват в "научно слисание" (понякога дори най-реномираните).
3) Прочитейки абстракта и въведението е пределно ясно, че статията е писана от
антиваксъри. Статията смърди от самото начало.
4) (свързано с "3") Подхода на авторите издава погрешено разбиране на науката
("ние знаем че ваксината е вредна и сега ще проврим всички възможни параметри
за да намерим някакво отклонение то нормата та да докажем тезата си")

За съжаление "4" е голям проблем в науката.

Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs …

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From: ddantg...@mail.ru (Nick)
Newsgroups: soc.culture.bulgaria
Subject: Re: Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The
role of G-quadruplexes, exosomes, and MicroRNAs …
Date: Tue, 19 Apr 2022 20:07:09 -0000 (UTC)
Organization: Aioe.org NNTP Server
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 by: Nick - Tue, 19 Apr 2022 20:07 UTC

On Tue, 19 Apr 2022 12:11:25 -0700 (PDT), Ivaylo Ivanov wrote:

> On Tuesday, April 19, 2022 at 12:39:26 PM UTC-4, Nick wrote:

>> On Tue, 19 Apr 2022 06:53:47 -0700 (PDT), Ivaylo Ivanov wrote:

>> >> Аз преди време бях пуснала подобна статия.
>> >> Ама нали съм конспиратор, сигурно никой не й обърна внимание.

>> > Освен хора с конспиративно мислене едва ли някой друг ще обърне
>> > внимание на статията по-горе. Не си струва дори да я коментирам.

>> браво бе, учения -- току-що обяви списание с импакт фактор за
>> конспиративно. има ли нещо между ушите или караш по добре познатия ти
>> почин -- „я солженицин не читал, но оссуждаю“?

> 1) "Food and Chemical Toxicology" не е особено престижно списание.
> 2) Занимавам се с наука и публикувам (и чета) научни сатии редовно -
> т.е. зная как "лайна" могат да се публикуват в "научно слисание"
> (понякога дори най-реномираните).

ами 1) и 2) си противоречат -- щом може да се публикуват „лайна“ в
престижни списания (това между другото е друга идиотщина), какво значение
има дали food and chemical toxicology не било престижно (според теб)?

> 3) Прочитейки абстракта и въведението е пределно ясно, че статията е
> писана от антиваксъри. Статията смърди от самото начало.

значи антиваксърите нямат право на мнение (това пък е трета идиотщина --
ваксъри <-> антиваксъри)?

> 4) (свързано с "3") Подхода на авторите издава погрешено разбиране на
> науката ("ние знаем че ваксината е вредна и сега ще проврим всички
> възможни параметри за да намерим някакво отклонение то нормата та да
> докажем тезата си")

аха, значи наличието на отклонения от нормата (защото те явно са намерили
такива) не доказва ли тяхната теза? или майната им на отклоненията от
нормата, важното е да ваксинираме (останалото между редовете оставям на
теб).

> За съжаление "4" е голям проблем в науката.

и какво точно е науката според теб?

не е ли точно това? хипотеза -> доказателства за нея –> теория?

ps ти да не пишеш от телефон?

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

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