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tech / sci.electronics.design / We thought we had just one genome. It turns out we have trillions.

SubjectAuthor
* We thought we had just one genome. It turns out we have trillions.Fred Bloggs
`* Re: We thought we had just one genome. It turns out we have trillions.Anthony William Sloman
 `* Re: We thought we had just one genome. It turns out we have trillions.Fred Bloggs
  `- Re: We thought we had just one genome. It turns out we have trillions.Anthony William Sloman

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We thought we had just one genome. It turns out we have trillions.

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Subject: We thought we had just one genome. It turns out we have trillions.
From: bloggs.f...@gmail.com (Fred Bloggs)
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 by: Fred Bloggs - Wed, 29 Nov 2023 16:41 UTC

That would be per individual and not across the entire population...

"Novel links between genes and disease are constantly emerging inside every tissue – yet have remained invisible to traditional genetics approaches. Illuminating beneficial and disease-causing variants can open vast potential to develop novel medicines that imitate or inhibit a variant’s impact."

This UK research startup has partnered with some with fairly sizeable and established corporations to bring this technology into practice soon.

https://quotient-tx.com/science

Re: We thought we had just one genome. It turns out we have trillions.

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Subject: Re: We thought we had just one genome. It turns out we have trillions.
From: bill.slo...@ieee.org (Anthony William Sloman)
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 by: Anthony William Slom - Thu, 30 Nov 2023 00:16 UTC

On Thursday, November 30, 2023 at 3:41:50 AM UTC+11, Fred Bloggs wrote:
> That would be per individual and not across the entire population...
>
> "Novel links between genes and disease are constantly emerging inside every tissue – yet have remained invisible to traditional genetics approaches. Illuminating beneficial and disease-causing variants can open vast potential to develop novel medicines that imitate or inhibit a variant’s impact."
>
> This UK research startup has partnered with some with fairly sizeable and established corporations to bring this technology into practice soon.
>
> https://quotient-tx.com/science

Everybody's genome gets corrupted as it gets copied - not by all that much, but there are billions of cells involved. We known that since we've known that we had a genome.

--
Bill Sloman, Sydney

Re: We thought we had just one genome. It turns out we have trillions.

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Subject: Re: We thought we had just one genome. It turns out we have trillions.
From: bloggs.f...@gmail.com (Fred Bloggs)
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 by: Fred Bloggs - Thu, 30 Nov 2023 15:15 UTC

On Wednesday, November 29, 2023 at 7:16:06 PM UTC-5, Anthony William Sloman wrote:
> On Thursday, November 30, 2023 at 3:41:50 AM UTC+11, Fred Bloggs wrote:
> > That would be per individual and not across the entire population...
> >
> > "Novel links between genes and disease are constantly emerging inside every tissue – yet have remained invisible to traditional genetics approaches. Illuminating beneficial and disease-causing variants can open vast potential to develop novel medicines that imitate or inhibit a variant’s impact."
> >
> > This UK research startup has partnered with some with fairly sizeable and established corporations to bring this technology into practice soon.
> >
> > https://quotient-tx.com/science
> Everybody's genome gets corrupted as it gets copied - not by all that much, but there are billions of cells involved. We known that since we've known that we had a genome.

We've 'known that' only in the most general sense. The new technology will allow them to know it down to the smallest detail. And the mutations occur for reasons other than being copied. The formation of mutations could be pre-programmed into the chromosome, as just one example. A brain in a disturbed mental state could even be orchestrating it.

>
> --
> Bill Sloman, Sydney

Re: We thought we had just one genome. It turns out we have trillions.

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Subject: Re: We thought we had just one genome. It turns out we have trillions.
From: bill.slo...@ieee.org (Anthony William Sloman)
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 by: Anthony William Slom - Thu, 30 Nov 2023 16:53 UTC

On Friday, December 1, 2023 at 2:15:10 AM UTC+11, Fred Bloggs wrote:
> On Wednesday, November 29, 2023 at 7:16:06 PM UTC-5, Anthony William Sloman wrote:
> > On Thursday, November 30, 2023 at 3:41:50 AM UTC+11, Fred Bloggs wrote:
> > > That would be per individual and not across the entire population...
> > >
> > > "Novel links between genes and disease are constantly emerging inside every tissue – yet have remained invisible to traditional genetics approaches. Illuminating beneficial and disease-causing variants can open vast potential to develop novel medicines that imitate or inhibit a variant’s impact."
> > >
> > > This UK research startup has partnered with some with fairly sizeable and established corporations to bring this technology into practice soon.
> > >
> > > https://quotient-tx.com/science
> > Everybody's genome gets corrupted as it gets copied - not by all that much, but there are billions of cells involved. We known that since we've known that we had a genome.
>
> We've 'known that' only in the most general sense.

We've known that cancer cells are cells with corrupted genomes since the 1960's. That's pretty specific.

> The new technology will allow them to know it down to the smallest detail.. And the mutations occur for reasons other than being copied. The formation of mutations could be pre-programmed into the chromosome, as just one example. A brain in a disturbed mental state could even be orchestrating it.

https://en.wikipedia.org/wiki/Transposable_element

We've known about transposable elements for a while. Barbara McClintock's discovery of them in 1951 earned her a Nobel Prize in 1983.

There's no mechanism that could let the brain orchestrate their activity. You really are remarkably ill-informed.

--
Bill Sloman, Sydney

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