In article <c65df24d-8305-49c4-9117-ac28af5dd9ddn@googlegroups.com>,
gnuarm.deletethisbit@gmail.com says...
>
> I was just negotiating terms and conditions with a clause about my company not being liable if the product is used in "high risk activities" such as nuclear plants. For some reason they felt the need to add an exception for my negligence, intentional misconduct or violation of law. They thought my objection to this was somehow
unreasonable!... What? I finally realized what they didn't understand (management types rather than engineers) was that the rules for design of products for high risk activities is very different where standard design practices very well could constitute illegality or negligence. I'm saying, "Don't do that!" and they are saying,
"But if we do...". After the explanation they did relent subject to their lawyers' approval.
>
>
>

I think Microsoft has a clause similar to that where they are not lible
for any problems you have with your computer if you use their software.
Lets them off the hook for all the people hacking into systems.

On 6/10/2021 5:52 PM, Fred Bloggs wrote:
> On Thursday, June 10, 2021 at 2:34:33 PM UTC-4, bitrex wrote:
>> On 6/8/2021 11:41 PM, Don Y wrote:
>>> On 6/8/2021 4:32 PM, Fred Bloggs wrote:
>>>
>>>> That kind of craziness should have been spelled out on that lengthy
>>>> information sheet that comes with each prescription. You really need
>>>> to sit
>>>> down and study that thing these days.
>>>
>>> The problem is that many just LIST the potential side effects.
>>> They give you no data to put the relative frequency (or personal
>>> likelihood) in proper perspective.
>>>
>>> What's worse is the catchall: "Don't take FOOBAR if you are
>>> allergic to FOOBAR..." WTF? And how will I know I'm allergic
>>> to a medication until I've been exposed to it? <rolls eyes>
>>>
>> My 83 y/o mother had a flareup of neuropathy in her feet this
>> springtime, she has this off and on but this spring for whatever reason
>> it flared up particularly bad.
>>
>> They prescribed Cymbalta, furiously expensive drug at $45/month supply
>> even with insurance (usual price over $300) all it did was gave her
>> insomnia and bad GI upset for two weeks. Stuff got thrown in the garbage
>> pretty fast.
>>
>> Thankfully the flareup seems to have eased off now, when the pain gets
>> bad she starts reading up on horror stories about foot amputation and
>> such, she's not diabetic so I think that's unlikely, though.
>>
>> Meantime she got her hands on some marijuana gummy bears, sensibly legal
>> in small quantity in my jurisdiction, and takes a sliver on the
>> occasions when the pain jumps off, works a trick to knock it down nearly
>> as well as an opiate it seems and she has a time, lol
>
> Sounds more like incipient gout.
>

Her doctor considered that but uric acid looks fine, all bloodwork they
did for e.g. diabetes, liver and kidney function looks OK in fact. at
5'6" 130 BMI doesn't seem a likely contributor.

Her PCP is leaning towards the idiopathic-type of lower extremities
neuropathy just caused by deterioration of the nerves due to old age.
Maybe something stem cells will be able to address, someday, but likely
not soon enough to help people of her generation, unfortunately

On 6/10/2021 5:42 PM, Don Y wrote:
> On 6/10/2021 11:34 AM, bitrex wrote:
>> My 83 y/o mother had a flareup of neuropathy in her feet this
>> springtime, she has this off and on but this spring for whatever
>> reason it flared up particularly bad.
>
> "slipped disc"?  (If you suspect this, you can actually look at charts
> that map the distribution of the various nerve exits from the spine
> to see which parts of the body are affected.
>
> <https://whyfiles.org/wp-content/uploads/2011/07/1nerve_regions.gif>
>
> (poor graphic)
>
> If, for example, the outside edge of the foot (only!) experiences
> symptoms, then S1 is the likely culprit.  The inside edge?  L5.
> If multiple areas, then likely not a disc issue.
>
> (The value to this sort of determination is it can help you
> change your behavior to avoid adding stresses to that portion
> of the spine)

Osteoarthritis in one knee is probably worsening the foot pain on one
side, but likely not the direct cause. She's waiting on a surgery for
that, the orthopedic guy says otherwise she seems in good health and
he's ready to move forward.

Said the operation is only about 45 min long so I don't think it's a
full knee replacement they'd be doing, maybe there's some kind of
composite they slip in there to prevent bone-on-bone contact. Not sure
of the details...

>> They prescribed Cymbalta, furiously expensive drug at $45/month supply
>> even with insurance (usual price over $300) all it did was gave her
>> insomnia and bad GI upset for two weeks. Stuff got thrown in the
>> garbage pretty fast.
>
> From what I hear, $45/month is pocket change.  I've a friend who spends
> hundreds per month on a medication for her eyes.  As she'd like to
> keep her vision, she hasn't much choice in the matter -- regardless of
> any side effects!

Seems high for a drug in its class, an SSRI pushing 20 years old that's
had generics available for some time.

<https://en.wikipedia.org/wiki/Duloxetine#Fibromyalgia_and_chronic_pain>

>> Thankfully the flareup seems to have eased off now, when the pain gets
>> bad she starts reading up on horror stories about foot amputation and
>> such, she's not diabetic so I think that's unlikely, though.
>
> Have a look at that chart.  You may discover that it's something that
> can be
> managed -- or avoided -- with behavioral changes.  Picking up (great)
> grandkids
> can possibly be a source of the problem.

I briefly wondered if it might be a side-effect of the vaccine, the jump
off in tingling/burning seemed to happen right around the same time.
Fortunately it seems to have eased off somewhat on its own...

>> Meantime she got her hands on some marijuana gummy bears, sensibly
>> legal in small quantity in my jurisdiction, and takes a sliver on the
>> occasions when the pain jumps off, works a trick to knock it down
>> nearly as well as an opiate it seems and she has a time, lol
>
> I don't think it actually has as much of an analgesic effect as it does
> a psychological effect -- distraction.  It's like the dentist giving
> you nitrous oxide -- to keep you from focusing on what he's doing!
>
> But, regardless, it's a relatively cheap fix.  Edibles are likely
> safer than inhalants.